Gadolinium-based contrast agents at 7 T: any impact of on human lymphocytes

The authors investigated the potentially toxic effect of different gadolinium-based contrast agents (GBCAs) in combination with 7-T MRI. By isolating and exposing lymphocytes analogously to iodinated contrast agents in combination with computed tomography, they found no damage to DNA or induction of γH2AX foci.

Article: The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

Authors: Björn Friebe, Frank Godenschweger, Mahsa Fatahi, Oliver Speck, Dirk Roggenbuck, Dirk Reinhold, Annika Reddig